Safflorite is a rare cobalt iron arsenide mineral with formula: (Co,Fe)As₂. Pure safflorite would be just CoAs₂, but iron is virtually always present. Safflorite is a member of the three-way substitution series of arsenides known as the loellingite or loellingite group. More than fifty percent iron makes the mineral loellingite whereas more than fifty percent nickel and the mineral is rammelsbergite. A parallel series of antimonide minerals exist.